Utility of Intraoperative Parathormone Assay as an Index to Successful Parathyroidectomy

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InTRAOPERATIvE PARAThORmOnE AssAy AnD RADIO- guIDED PARAThyROIDEcTOmy In PATIEnTs wITh PRImARy hIPERPARAThyROIDIsm

The outcome of surgical treatment of primary hyperparathyreoidism (PHP) is largely dependent on the radicality of the operation. This is sometimes difficult due to abnormal location of the glands. The use of intraoperative parathormone assay (IOPTH) and a handheld gamma-ray detector (HGRD) might influence the outcome of treatment. The aim of the study was to assess the feasibility of intraopera...

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Concise parathyroidectomy: the impact of preoperative SPECT 99mTc sestamibi scanning and intraoperative quick parathormone assay.

BACKGROUND Results of initial operation for sporadic primary hyperparathyroidism are generally excellent, yet today there is pressure to improve outcome and resource utilization. METHODS We designed a prospective longitudinal cohort study comparing two approaches to concise parathyroidectomy. Strategy A was defined as the palpation method for selective unilateral exploration. Strategy B was d...

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Normocalcemic parathormone elevation after successful parathyroidectomy: long-term analysis of parathormone variations over 10 years.

BACKGROUND The long-term significance of normocalcemic parathormone elevation (NPE) after successful parathyroidectomy for sporadic primary hyperparathyroidism remains unclear. METHOD Of 239 consecutive patients who underwent targeted parathyroidectomy with intraoperative parathormone monitoring, 96 were followed for ≥ 10 years. NPE was defined as a normal serum calcium level and parathormone...

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Intraoperative PTH cutoff definition to predict successful parathyroidectomy in secondary and tertiary hyperparathyroidism.

UNLABELLED In order to improve success rates in surgery of renal hyperparathyroidism, we evaluated intraoperative PTH (IOPTH) measurement utility. METHOD 86 patients underwent total parathyroidectomy with intramuscular presternal autotransplantation from 04/2000 to 10/2009 and were followed for 26.5 months on average (prospective cohort). Patients were divided in secondary (SHPT) and tertiary...

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Focused parathyroidectomy without intra-operative parathormone monitoring: The value of PTH assay in preoperative ultrasound guided fine needle aspiration washout

BACKGROUND The accurate identification of hyperfunctioning parathyroid (HP) gland is the only issue for definitive surgical treatment in primary hyperparathyroidism (pHPT). Various imaging and operative techniques have been proposed to confirm the localization of the diseased gland. Nevertheless, none of these methods proved to be the gold standard. The presented study aimed to assess the value...

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ژورنال

عنوان ژورنال: Journal of Hormones

سال: 2014

ISSN: 2356-7449,2314-6222

DOI: 10.1155/2014/750401